About the project
Limitations of neural plasticity in mammals make them vulnerable to insult with irreversible damage. We have discovered that the salmon undergoes a unique dramatic period of structural and chemical change mid-life during parr-smolt transformation (smoltification).
The overall objective of the project is to integrate endocrine and neural transcriptomics together with unique salmon brain models to 1) elucidate triggers and regulators of neural development and 2) determine molecular mechanisms that limit/restrict the degree of neural development. Candidate systems will be functionally tested to determine their efficacy in regulating the development.